Royal Air Force Typhoon FGR4s have operated alongside France's air force in a combined operation targeting an underground arms cache in Syria used by the IS group, according to the UK's MoD.
The facility, identified by reconnaissance, was assessed as containing munitions and bombs, the release indicated, and was positioned in mountainous terrain just above the historic site of Palmyra in Syria's central region.
"Our aircraft used laser-guided Paveway IV weapons to hit a number of entry passages down to the depot... initial indications suggest the target was engaged successfully," the ministry announced.
There was no evidence of any civilian casualties in the operation on Saturday evening and each participating jet returned to base without incident, the ministry further stated.
The British jets were backed up by a Voyager aerial refuelling aircraft.
Daesh - also known as Daesh - imposed militant control over significant areas in both Syria and Iraq before its territorial defeat in 2019.
"This strike underscores British leadership, and commitment to stand shoulder to shoulder with allied nations, to stamp out any resurgence of Daesh and their dangerous and violent ideologies in the Middle East," Britain's Defence Chief the minister stated.
RAF aircraft have conducted surveillance missions over Syria to "prevent any efforts to regroup" of the group after its routing at the Baghuz confrontation in 2019, the ministry said.
"I want to thank every member of our armed forces participating in this operation for their professionalism and their courage," he said. "They were among numerous UK service members on duty over the holidays. This mission, to take out dangerous terrorists who threaten our safety, highlights how UK forces are always on standby, continuously, protecting the UK at home and strong abroad."
Last December, the United States armed forces executed what it called a "massive strike" on Daesh sites in Syria, after an ambush claimed the lives of two US troops and a civilian interpreter in Palmyra.
The U.N. estimates Islamic State still has roughly 5-7 thousand fighters in both countries.
